Borrellecture: Nuclear Pore Complexes

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When?
December 16, 2024 5:00 PM
Where?
FGB 5612.0142

What?

On the 16th of December, Physica is inviting professor Patrick Onck to speak at a borrellecture on NPC’s (nuclear pore complexes), in which we will delve into the microscopic world of proteins aided with beautiful visuals!

The nuclear pore complex (NPC) is a large protein complex in the nuclear membrane and the sole gateway for molecules to leave or enter the nucleus. Intrinsically disordered proteins act as gatekeepers of the NPC by providing a selective permeability barrier. To resolve the puzzling paradox of providing both transport and barrier functionality within a single protein complex, his group developed a coarse-grained molecular dynamics framework at amino acid resolution. Recent results regarding the quest to uncover the fundamental physical mechanisms that are responsible for selective transport will be discussed, while we will peek into nuclear pores of living cells with a computational microscope.

Sound interesting? Then head on over to FGB 5612.0142 at 17:00 on the 16th of December for some free drinks, snacks and a good time! See you there :)